Faculty Details

Profile

Dr. Prabhakar Singh received his MSc in Biochemistry (2004) from Banaras Hindu University (BHU), Varanasi and PhD (2012) in Anatomy from All India Institute of Medical Sciences (AIIMS), New Delhi, India. He was a visiting researcher at A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland during 2009-2010. He worked as a postdoctoral fellow at Kansas City VA Medical Center, Kansas City, Missouri (2012-2016) and University of Kansas Medical Center, Kansas, USA (2016-2017). He was employed as a Research Scientist at Kansas City VA Medical Center, Missouri, USA from June 2017 to March 2020. He joined the Department of Anatomy, AIIMS as an Assistant Professor of Electron Microscopy in 2020. 

https://sites.google.com/aiims.edu/drprabhakarsingh/

Research

Research Details Webpage Link

Publication

Zhang Q, Singh P, Peng DW, Peng EY, Burns JM, Swerdlow RH, Suo WZ. Proactive M2 Blockade Prevents Cognitive Decline in GRK5-Deficient APP Transgenic Mice via Enhancing Cholinergic Neuronal Resilience. J Biol Chem. 2024 Aug 2:107619.

Sonter S, Dwivedi MK, Mishra S, Singh P, Kumar R, Park S, Jeon B, Singh PK. In vitro larvicidal efficacy of Lantana camara essential oil and its nanoemulsion and enzyme inhibition kinetics against Anopheles culicifacies. Scientific Reports. 2024;  14, 16325. 

Mondal S, Sharma B, Majumdar A, Tiwari S, Maurya PK, Gupta A, Singh SP, Singh P. Sample Preparation and Visualization Protocol for Electron Microscopy–Based Analysis of Cyanobacteria. In: Singh SP. ed. Methods in Cyanobacterial Research. Taylor & Francis CRC Press; 2024; 170-181

Bhange K, Kumar RR, Singh P, Chaturvedi V. Feather Protein Hydrolysate mediated synthesis of silver nanoparticles and assessment of anti-microbial potential of silver nanoparticle-treated silk cloth. Indian Journal of Biochemistry and Biophysics. 2023; 60:581-588 

Roy S, Roy UG, Ghorai U, Saha SK, Singh P, Mukhopadhyay A, Tripathy B. Ultrastructural variations of the sagittae in two Anabantiformes fishes: Anabas testudineus (Bloch, 1792) and Trichogaster fasciata (Bloch & Schneider, 1801). 2023; 60:610-621 [Impact Factor 1.9]

Rafat S, Singh P, Pandey KK, Almatroodi SA, Alsahli MA, Almatroudi A, Rahmani AH, Dev K. SMAC Mimetic BV6 Co-Treatment Downregulates the Factors Involved in Resistance and Relapse of Cancer: IAPs and Autophagy. Biology. 2022; 11(11):1581

Dastidar DG, Singh P, Bhattacharjee R, Ghosh D, Banerjee M, Biswas S, Mukherjee SK, Mandal S. Development of Copper Nanoparticle Conjugated Chitosan Microparticle as a Stable Source of 2nm Copper Nanoparticle Effective against Methicillin- resistant Staphylococcus aureus. Pharm Nanotechnol. 2022; 10(4):310-326. 

Kaur J, Ghosh S, Singh P, Dwivedi AK, Sahani AK, Sinha JK. Cervical Spinal Lesion, Completeness of Injury, Stress, and Depression Reduce the Efficiency of Mental Imagery in People With Spinal Cord Injury. Am J Phys Med Rehabil. 2022 Jun 1;101(6):513-519. 

Ghosh S, Sinha JK, Khan T, Devaraju KS, Singh P, Vaibhav K, Gaur P. Pharmacological and therapeutic approaches in the treatment of epilepsy. Biomedicines 2021, 9, 470. 

Chaturvedi V, Kabale, P, Singh P. Biofabrication of Silver Oxide Nanoparticles (SO-NP) by autolysate of Pseudomonas mendocina PM1, and assessment of its antimicrobial/anti-biofilm potential. Indian Journal of Biochemistry and Biophysics, 2021; 58 (4), 373-380.

Chaudhary S, Rai P, Sesham K, Kumar, Singh P, Nag TC, Chaudhuri P, Trikha, Yadav SC. Microscopic imaging of bronchoalveolar fluids of COVID-19 positive intubated patients reveals the different level of SARS-CoV-2 infection on oral squamosal epithelial cells. Indian Journal of Biochemistry & Biophysics. 2021; 58 (3), 196-207 

Singh P, Peng DW, Suo WZ. Stereological estimation of cholinergic fiber length in the Nucleus Basalis of Meynert of the mouse brain. J Vis Exp. 2020;(156):e60405.

Suo WZ, Peng DW, Singh P, Ding XF. A standardized anxiety quotient in elevated open platform task quantifies rodent anxiogenic tendency with improved reliability and sensitivity. Neuroscience. 2019; 423:12-17. 

Singh P, Das TK. Ultrastructural localization of 4-hydroxynonenal adducts in fluoride exposed cells: protective role of dietary antioxidants. Fluoride 2019; 52 (1): 49-58

Khristi V, Chakravarthi VP, Singh P, Ghosh S, Pramanik A, Ratri A, Borosha S, Roby KF, Wolfe MW, Rumi MAK. ESR2 regulates granulosa cell genes essential for follicle maturation and ovulation. Mol Cell Endocrinol. 2018; 474:214-226.

Khristi V, Chakravarthi VP, Singh P, Ghosh S, Pramanik A, Ratri A, Borosha S, Roby KF, Wolfe MW, Rumi MAK. Differentially regulated genes in Esr2-mutant rat granulosa cells. Data in brief 2018;19,1008-1011

Rumi MAK, Singh P, Roby KF, Zhao X, Iqbal K, Ratri A, Lei T, Cui W, Borosha S, Dhakal P, Kubota K, Chakraborty D, Vivian JL, Wolfe MW, Soares MJ. Defining the role of estrogen receptor beta in the regulation of female fertility. Endocrinology 2017;158 (7): 2330-2343

Khandelwal VKM, Singh P, Ravingerova T, Gregory M, Gandhi H. Comparison of different osmotic therapies in a mouse model of traumatic brain injury. Pharmacological Reports 2017;69 (1) 176-184

He M, Singh P, Cheng S, Zhang Q, Peng W, Premont R, Morgan D, Burns J, Swerdlow R, Suo W. GRK5 deficiency leads to selective basal forebrain cholinergic neuronal vulnerability. Scientific Reports 2016; 6:26116

Singh P, Zhang Q, Peng W, Suo W. GRK5 renders susceptibility to intermittent hypoxia-induced cognitive impairment. Behavioral Brain Research 2016;302: 29-34

Current Lab Members

Sl	Photo	Details
1		Name- Yogesh Sharma Position- PhD Student Joining Date- 1 oct 2023 Qualification- MSc Anatomy Projects- The effects of modulation of cholinergic transmission on amyloid beta- induced neurodegeneration in rat brain.
2		Name- Sumant Kumar Position- PhD Student Joining Date- 8th October 2024 Qualification- Graduation from BHU, MSc Neuroscience form University of Madras Projects- Effect of maternal chronic hypoxia on cholinergic system and cognitive function of offspring.
3		Name- Dr. Hari Prasad Position- MD Student Joining Date- Qualification- Projects-
4		Name- Dr. Subhankar Roy Position- MD Student Joining Date- Qualification- Projects-